Can creatine treat myotonic dystrophy?

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Can creatine treat myotonic dystrophy?

  • Myotonic dystrophy is an inherited chronic systemic disease that is mainly characterized by muscle wasting, myotonia (delayed muscular relaxation after contraction), cataract and heart conduction defects.

Creatine have no to little effects on myotonic dystrophy patients as shown by the following studies:

  • A study was done in 2004 on 34 patients. They were divided into two groups; the first supplemented with creatine and the other with placebo. Creatine supplementation does not have any effects on muscle strength, body composition, or activities of daily living in patients with myotonic dystrophy.1
  • Muscle pain in some patients and some other measured mildly improved in many patients taking creatine supplements compared to placebo group.2
  • A study was done in 2002 on the benefits of creatine supplementation on quality of life and muscle strength for myotonic dystrophy patients. After the 8 weeks’ period of the study, no positive or negative effects were found on muscle strength and daily-life activities.3
benefits

REFERENCES

  1. Tarnopolsky M, Mahoney D, Thompson T, Naylor H, Doherty TJ. PubMed. Bethesda, Maryland: National Center for Biotechnology Information; 2004. http://www.ncbi.nlm.nih.gov/pubmed/14694498. Accessed May 07, 2016.
  2. Schneider-Gold C, Beck M, Wessig C. PubMed. Bethesda, Maryland: National Center for Biotechnology Information; 2003. http://www.ncbi.nlm.nih.gov/pubmed/12578937. Accessed May 07, 2016.
  3. Walter MC, Reilich P, Lochmüller H, et al. PubMed. Bethesda, Maryland: National Center for Biotechnology Information; 2002. http://www.ncbi.nlm.nih.gov/pubmed/12529796. Accessed May 07, 2016.
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